Chromosomal Microarray Analysis (CMA) is a powerful diagnostic tool used to detect chromosomal abnormalities that may cause developmental delays, congenital anomalies, or other genetic conditions in children. CMA is particularly useful in identifying submicroscopic deletions and duplications (copy number variations, or CNVs) that are not detectable by traditional karyotyping.
CMA is recommended for children with unexplained developmental delays, intellectual disabilities, autism spectrum disorders, congenital anomalies, or other complex conditions where a chromosomal cause is suspected.
Conditions Diagnosed:
- Developmental Delay/Intellectual Disability: Identifies CNVs associated with neurodevelopmental disorders.
- Autism Spectrum Disorders: Detects genetic variations that may contribute to autism.
- Congenital Anomalies: Identifies chromosomal imbalances that cause physical malformations.
- Rare Genetic Disorders: Helps diagnose rare conditions by detecting unique or recurrent CNVs.