Breast and Ovarian cancers are the most frequently observed cancer types in women and within all cancertypes they rank as the 5th most common. Hereditary forms of breast and ovarian cancer account for 5-10% of all cases diagnosed and this is found to be clearly associated with the mutations in BRCA1/2 genes.
When the BRCA testing should be performed?
BRCA1 and BRCA2 testing is strongly recommended when a patient’s personal or family history includes any of the following conditions:
- Women diagnosed with breast cancer under the age of 50
- Ovarian cancer at any age
- Cancer development in the same breast twice
- Detection of cancer in both breasts
- Triple-negative breast cancer (estrogen receptor, progesterone receptor and HER2 negative)
- History of pancreatic cancer together with breast or ovarian cancer in the same individual or in his/her relatives
- History of breast cancer in two or more relatives
- BRCA1 or BRCA2 mutation that is previously identified in the family
- Breast cancer in male
- Individuals having a male relative who is diagnosed with breast cancer
For more information download the PDF brochure