Osteoprosis

Studies have revealed some polymorphisms related to reduction in bone mineral density (BMD) and fracture risk. Today, Collagen Type 1, vitamin D, estrogen and calcitonin receptor gene regions are validated as polymorphic sites.

These polymorphisms play important roles to predetermine clinical course of the disease and to determine effective supportive treatments. These differences comprise 6 distinct polymorphisms at 4 different gene regions and they are also important marks to design proprietary treatments.

"The results suggest a helical structure which must be very closely packed containing probably 2, 3 or 4 coaxial nucleic acid chains per helical unit and having the phosphate groups near the outside."

Rosalind Elsie Franklin