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Unlike nuclear DNA, mitochondrial DNA, which plays a very significant role in cellular energy cycle, resides in the cytoplasm and...
According to Mendelian Genetics; single gene diseases arise from defect on a single gene situated on the chromosomes. These defects...
Autosomal recessive disorders comprises nearly one third of single gene diseases. For autosomal recessive diseases to be functional, a single...
A functional alteration in one of the gene couple located on the same locus is enough for the emergence of...
Because the disease is inherited by sex chromosomes ( X chromosome), except for rare cases, diseases are determined only in...
Disease can be observed both at boys and girls and the pattern of inheritance resembles the autosomal dominant inheritance. However,...
Chromosomal disorders usually have lethal effect and incidence of occurrence is between 0,5% and 0,7% in alive newborns. These chromosomal...
Normal human somatic cells include 46 chromosomes. If the number chromosomes is 23 and its multiples, then it cannot be...
The most frequently observed form of chromosomal rearrangements is translocation (reciprocal or robertson translocation) that occurence frequency is 1 out...
Consanguineous marriage is the marriage between partners having kinship to each other. Primary consanguineous marriage is defined as a union...
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