X-Linked Dominant Diseases

Disease can be observed both at boys and girls and the pattern of inheritance resembles the autosomal dominant inheritance. However, as different from autosomal dominant inheritance, since father  with this disorder transmit his Y chromosomes to his sons, therefore his sons can never be afflicted via their paternal side. On the other hand, for the mothers with such genetic disorder, her sons and daughters have equal chance to get this trouble-bearing X-linked chromosome from their mother with 50 % by chance.

"The discovery of the structure of DNA transformed not only biology but also our understanding of what it means to be human."

Francis Crick